It was founded by Mariscal Andrés de Santa Cruz on November 5, 1832; and is one the first universities founded in Bolivia after the San Francisco Xavier University from Chuquisaca and the University of San Andrés from La Paz. The University currently offers 99 undergraduate programs in 18 faculties that are mainly established in Cochabamba city. According to uniRank, the University of San Simón ranks second among Bolivian universities, and second according to Webometrics  and the QS World University Rankings.
- "MEMORANDUM OF UNDERSTANDING Between Byucksan Engineering Co. Ltda. And University of San Simon Cochabamba - Bolivia." (Archive) University of San Simón. Retrieved on December 26, 2012. Second page of English agreement. "UNIVERSIDAD MAYOR DE SAN SIMON located at Av. Ballivian 591, Cochabamba-Bolivia."
- "Inicio." University of San Simón. Retrieved on December 26, 2012. "La Universidad Mayor de San Simón fue fundada mediante ley de 5 de noviembre de 1832 por el Mariscal Andrés de Santa Cruz."
- University of San Simón (in Spanish)
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