Upsher-Smith Laboratories


Upsher-Smith Laboratories, LLC is an American pharmaceutical company based in Maple Grove, Minnesota that has delivered generic medications for nearly a century. Upsher-Smith is a part of Japan-based Sawai Pharmaceutical, Co. Ltd.

Upsher-Smith Laboratories
TypePublicly traded
HeadquartersMaple Grove, Minnesota, United States
Productsgeneric drugs


  • Maple Grove, Minnesota: Corporate Headquarters
  • Plymouth, Minnesota: Manufacturing and R&D
  • Denver, Colorado: Manufacturing and R&D


Founded in 1919 as a maker of digitalis drugs,[1] Upsher-Smith has traditionally focused on the manufacture of generic medications. In 2017, after owning and operating Upsher-Smith for 47 years, the Evenstad family made the decision to sell the largest part of their company, the generics business, to Sawai Pharmaceutical Co., Ltd., a large publicly traded generics company in Japan that had been seeking entry into the U.S. market.[2]

Upsher-Smith’s non-generic pharmaceuticals businesses Proximagen, Pairnomix and MOBĒ remained with ACOVA, a holding company owned by the Evenstads.


Upsher-Smith Supplies CVS Pharmacies and offers generic pharmaceuticals to treat the following disease states:[3]

  • Hypertension
  • High Cholesterol
  • Influenza
  • Epilepsy
  • Congestive Heart Failure
  • Blood Clots
  • Alzheimer's Disease
  • Depression
  • Overactive Bladder
  • Heart Arrhythmia
  • Schizophrenia
  • Multiple Sclerosis
  • Low Testosterone


  1. ^ "Upsher-Smith History".
  2. ^ "Sawai Pharmaceutical Completes Acquisition of Upsher-Smith Laboratories Generics Business". May 31, 2017.
  3. ^ "Upsher-Smith Products".