Ushio may refer to:

• Japanese destroyer Ushio, two IJN ships
• Ushio Okazaki, a fictional character from Clannad
• Ushio (magazine) (潮), a Japanese magazine which has a strong connection with Soka Gakkai
• Ushio Shuppansha (潮出版社), the Japanese publisher
• Ushio Inc., partner of Jenoptik AG in an Intel funding for an EUV-Lithography joint-venture
• Ushio, Inc. (ウシオ電機), a publicly traded Japanese company with its headquarters in Tokyo
• Ushio and Tora, a 1990 Japanese manga
• Ushio Shimabara, one of main characters of Neo Ranga
• Ushio Kofune, a fictional character from Summer Time Rendering