Vancouver Technical School opened in September 1916 as a boys-only school and was located in the basement of King Edward Highschool on 12th and Oak. It was the province's first vocational school and was led by J. George Lister, who would later be called the "Founder of Technical Education in BC.^[2] The school then moved to the Labour Temple, located on the corner of Homer and Dusmuir.^[3]

As enrollment grew, plans were developed for a modern technical school along Broadway. The building was designed by architects Townley and Matheson to include large technical shops, laboratories, cafeteria, auditorium, gymnasium, and swimming pool. However, the swimming pool was never completed due to lack of funds. The school moved to the new building in 1928, where it is located to this day. Girls were admitted into the school starting in 1940 and were given their own wing on the East side.

Major seismic upgrades to the school's five buildings began in 2005 and was completed in 2008 at a cost of $40 million.^[4] The seismic upgrades reduced the available floorspace, leading to the relocation of classroom and workshops. Classrooms and workshops were relocated or replaced during the upgrade as there was less floor space available. this reduced the school's capacity from 2,100 students to 1,700. The auditorium's interior was also renovated during the upgrade, with the funds being raised by students' parents.^[5]

One of the school's founders (and principal from 1930 until 1944), James George Sinclair, is also the great-grandfather of 23rd Canadian Prime Minister Justin Trudeau.^{[citation needed]}

Vancouver Technical offers two mini school programs.

Summit is a five-year mini school program as of 2018, which focuses on enriching the four academic courses: Math, Science, Social Studies and English. The Summit program offers accelerated sciences and mathematics, with students completing Chemistry 11 and Pre-Calculus 11 in grade 10. Students in the Summit program engage in many extra-curricular activities including a three-day camp at the beginning of the school year, and opportunities to travel to Europe.^{[6][unreliable source?]}

Flex Humanities is a mini-school that integrates Philosophy, World Literature, History, Fine Arts, Film and Media Studies, and Integrated Arts and Technology from grades 8 – 12. In grade 12, the students have the opportunity to participate in a major culminative field study; in past years, this trip has involved Quebec City/Montreal or New York.

With its seismic upgrade from 2005 - 2008, many classrooms were moved around and their 500 wing was demolished. With this, Vancouver Technical was a recipient to a $1,000,000 artificial turf field that was approved in 2006.^[7] Tennis courts were built off Slocan St. and Vancouver Technical is set to receive Vancouver's first regulation Track and Field Training Facility.^[8]

• Greg Joy, Olympic medalist - track and field
• Sam Sullivan, former mayor of the city of Vancouver, former MLA for Vancouver False Creek
• Bowinn Ma, MLA for North Vancouver-Lonsdale
• John Ferguson (1938–2007), NHL player/coach^{[citation needed]}
• Dean Malkoc, NHL player for the Vancouver Canucks, Boston Bruins, and New York Islanders
• Julia Grosso, Soccer player for Canadian women's national team and 2020 Olympic Gold Medallist
• Milton Wong, Member of the Order of Canada, Order of British Columbia, Chancellor, Simon Fraser University, Business Laureates of British Columbia Hall of Fame, philanthropist

• Exterior shots of the school were used in the CW's television series Smallville to represent Smallville High School, Clark Kent's alma mater during adolescence. The school was also used as a filming location in Scary Movie, Paycheck, Supernatural, iZombie, Psych, Supergirl, The Killing, and She's the Man starring Amanda Bynes and Channing Tatum.^[9]

• Vancouver Technical Secondary School
• Vancouver School Board - Vancouver Technical Secondary
• Van Tech students playing Spanish Fever
• Van Tech Music Program