William Henry Harrison (1773–1841) was the president of the United States in 1841.

William Henry Harrison may also refer to:

• William Henry Harrison (New Zealand politician) (1831–1879)
• William Henry Harrison (Georgia politician) (fl. 1843–1871), African-American representative in the Georgia Legislature during the Reconstruction Era
• William Henry Harrison (cricketer) (1866–1936), English cricketer
• William Henry Harrison (Canadian politician) (1880–1955)
• William Henry Harrison (businessman) (1892–1956), American general
• William Henry Harrison III (1896–1990), American representative and Indiana and Wyoming state legislator
• William Henry Harrison (architect) (1897–1988), American architect in California
• William H. Harrison (Wyoming politician) (1894–1991), Wyoming state representative