William Stern may refer to:

• William Stern (businessman) (1935–2020), owner of the British Stern Group of companies
• William Stern (psychologist) (1871–1938), German psychologist and philosopher
• William Stern, father of American surrogate child Baby M
• William Joseph Stern (1891–1965), physicist and jet engine developer
• William M. Stern, rabbi at Temple Sinai in Oakland, California
• Bill Stern (1907–1971), American actor and sportscaster