There have been four baronetcies created for persons with the surname Willoughby, three in the Baronetage of England and one in the Baronetage of Great Britain. One creation is extant as of 2008.

The Willoughby Baronetcy, of Risley in the County of Derby, was created in the Baronetage of England on 29 June 1611 for Henry Willoughby. The title became extinct on his death in 1649.^[1] By his first wife Elizabeth Knollys, daughter of the privateer Sir Henry Knollys, he had a daughter Elizabeth, who married the noted antiquarian Sir Simonds d'Ewes.

The Willoughby Baronetcy, of Selston in the County of Nottingham, was created in the Baronetage of England on 4 August 1660 for William Willoughby. The title became extinct on his death in 1671.

The Willoughby Baronetcy, of Wollaton in the County of Nottingham, was created in the Baronetage of England on 7 April 1677. For more information, see the Baron Middleton.

The Willoughby Baronetcy, of Baldon House in the County of Oxford, was created in the Baronetage of Great Britain on 8 December 1794 for Christopher Willoughby. The third Baronet sat as Member of Parliament for Yarmouth, Newcastle-under-Lyme and Evesham. The fourth Baronet represented Leominster in the House of Commons. The title became extinct on the death of the fifth Baronet in 1918.