After twenty years as a minor party, the Yukon Liberal Party won the 2000 general election and formed a government under Premier Pat Duncan. The government, however, was reduced to minority government status. Duncan called a snap election for November 2002 in the hope of regaining her government's majority. The party was almost completely wiped out, however, by the Yukon Party. Duncan won the Liberals' sole seat in the Yukon Party's landslide.

The Liberal Party remained in opposition until the 2016 general election where the party went from third place in the legislature to majority government with its leader, Sandy Silver, becoming Premier.

• Iain MacKay 1978–1981
• Ron Veale 1981–1984
• Roger Coles 1984–1986
• Jim McLachlan 1986–1989
• Paul Thériault 1989–1992
• Jack Cable 1992–1995 (interim)
• Ken Taylor 1995–1997
• Jack Cable 1997–1998 (interim)
• Pat Duncan 1998–2005
• Arthur Mitchell 2005–2011
• Darius Elias 2011–2012 (interim)
• Sandy Silver 2012–2023
• Ranj Pillai 2023–present

• Yukon Liberal Party
• Yukon Liberal Caucus
• Yukon Federal Liberal Association Riding
• Constitution of Yukon liberal party (PDF)

• List of political parties in Canada
• List of premiers of Yukon
• List of Yukon Leaders of Opposition