3-Hydroxyaspartic acid (three letter abbreviation: Hya) also known as beta-hydroxyaspartic acid is derivative of aspartic acid which has been hydroxylated at position-3. The adjacent image shows L-threo-3-Hydroxyaspartate. The conjugated acid of 3-hydroxyaspartic acid is 3-hydroxyaspartate.
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Preferred IUPAC name
(2S)-2-Amino-3-hydroxybutanedioic acid | |
Other names
(2S)-2-Amino-3-hydroxysuccinic acid
3-Hydroxyaspartic acid Beta-hydroxyaspartic acid | |
Identifiers | |
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3D model (JSmol)
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ChEBI |
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KEGG |
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PubChem CID
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UNII |
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Properties | |
C4H7NO5 | |
Molar mass | 149.102 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Similarly to proteinogenic isoleucine and threonine, 3-hydroxyaspartic acid contains two chiral centers. As such, it can exist in 4 stereoisomers, which form two pairs of enantiomers.
The Hya amino acid residue is sometimes contained in EGF-like domains such as Vitamin K-dependent coagulation plasma proteins including protein C.[1]
D-threo-3-Hydroxyaspartate is a part of the siderophore ornibactin.[2]