Alizarin Red S (also known as C.I. Mordant Red 3, Alizarin Carmine, and C.I 58005.[1]) is a water-soluble sodium salt of Alizarin sulfonic acid with a chemical formula of C
14H
7NaO
7S.[2][1] Alizarin Red S was discovered by Graebe and Libermann in 1871.[2] In the field of histology alizarin Red S is used to stain calcium deposits in tissues,[3][4] and in geology to stain and differentiate carbonate minerals.[3]
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IUPAC name
3,4-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid
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Other names
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Identifiers | |
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3D model (JSmol)
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ChEBI |
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ChemSpider |
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ECHA InfoCard | 100.004.530 |
EC Number |
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PubChem CID
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C14H7NaO7S | |
Molar mass | 342.253 g/mol |
Appearance | yellow-orange powder |
Soluble in water and ethanol | |
Hazards | |
Safety data sheet (SDS) | [1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Alizarin Red S is used in histology and histopathology to stain, or locate calcium deposits in tissues.[1][3][4] In the presence of calcium, Alizarin Red S, binds to the calcium to form a Lake pigment that is orange to red in color.[4] Whole specimens can be stained with Alizarin Red S to show the distribution of bone, especially in developing embryos.[4] In living corals alizarin Red S has been used to mark daily growth layers.[5]
In geology, Alizarin Red S is used on thin sections, and polished surfaces to help identify carbonate minerals which stain at different rates.[6]