Putative gonadotropin-releasing hormone II receptor is a protein that in humans is encoded by the GNRHR2 gene.[3][4]
GNRHR2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | GNRHR2, GnRH-II-R, gonadotropin releasing hormone receptor 2 (pseudogene) | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | GeneCards: GNRHR2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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The receptor for gonadotropin-releasing hormone 2 (GnRH2) is encoded by the GnRH2 receptor (GnRHR2) gene. In non-hominoid primates and non-mammalian vertebrates, GnRHR2 encodes a seven-transmembrane G protein-coupled receptor. However, in humans, the N-terminus of the predicted protein contains a frameshift and premature stop codon. In humans, GnRHR2 transcription occurs but whether the gene produces a functional C-terminal multi-transmembrane protein is currently unresolved. Alternative splice variants have been reported. An untranscribed pseudogene of GnRHR2 is also on chromosome 14.[4]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.