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GPR125

Summary

Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene[4][5] (previously Gpr125).

ADGRA3
Identifiers
AliasesADGRA3, PGR21, TEM5L, GPR125, adhesion G protein-coupled receptor A3
External IDsOMIM: 612303 MGI: 1917943 HomoloGene: 19235 GeneCards: ADGRA3
Orthologs
SpeciesHumanMouse
Entrez

166647

70693

Ensembl

n/a

ENSMUSG00000029090

UniProt

Q8IWK6

Q7TT36

RefSeq (mRNA)

NM_145290

NM_133911

RefSeq (protein)

NP_660333

NP_598672

Location (UCSC)n/aChr 5: 50.12 – 50.22 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

References edit

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029090 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (Feb 2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini". Biochem Biophys Res Commun. 301 (3): 725–34. doi:10.1016/S0006-291X(03)00026-3. PMID 12565841.
  5. ^ "Entrez Gene: GPR125 G protein-coupled receptor 125".

Further reading edit

  • Seandel M; et al. (2007). "Generation of functional multipotent adult stem cells from GPR125+ germline progenitors". Nature. 449 (7160): 346–50. Bibcode:2007Natur.449..346S. doi:10.1038/nature06129. PMC 2935199. PMID 17882221.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Yamamoto Y, Irie K, Asada M, et al. (2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein". Oncogene. 23 (22): 3889–97. doi:10.1038/sj.onc.1207495. PMID 15021905.
  • Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.