β-Guanidinopropionic acid, also referred to as guanidinopropionic acid, beta-guanidinopropionic acid or β-GPA, is a dietary supplement.
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IUPAC name
3-Carbamimidamidopropanoic acid[1]
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Other names
3-(Diaminomethylideneamino)propanoic acid[citation needed]
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Identifiers | |
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3D model (JSmol)
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3DMet |
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1705262 | |
ChEBI |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.005.937 |
EC Number |
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KEGG |
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MeSH | guanidopropionic+acid |
PubChem CID
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RTECS number |
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C4H9N3O2 | |
Molar mass | 131.135 g·mol−1 |
Appearance | White crystals |
Odor | Odourless |
log P | −1.472 |
Acidity (pKa) | 4.219 |
Basicity (pKb) | 9.778 |
Hazards | |
GHS labelling: | |
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H315, H319, H335 | |
P261, P305+P351+P338 | |
Related compounds | |
Related alkanoic acids
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Related compounds
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Dimethylacetamide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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β-Guanidinopropionic acid is a white crystalline powder soluble in water (50 mg/ml-clear, colorless solution).[2]
Studies on animals (rats, monkeys, hamsters) show that acidic guanidine derivatives such as β-GPA can ameliorate hyperglycemia in animal models of noninsulin-dependent diabetes.[3]
Though the oral availability of β-GPA is well established, the basic uptake mechanism has not been studied yet.[4]