Henriette Wyeth was born in Wilmington, Delaware, into an artistic family. Wyeth was the eldest of the five children of noted illustrator N.C. Wyeth and his wife Carolyn Bockius.^[2] Her siblings Carolyn and Andrew also became artists, and all three studied with their father. Andrew Wyeth became the most well-known artist of this family.^[3]

Henriette contracted polio at age 3, which altered her health and use of her right hand. As a result, she learned to draw with her left hand and paint with her right.^[4] She grew up on the family farm in Chadds Ford, Pennsylvania, and attended local Quaker schools.^[5] She and her siblings were eventually homeschooled because their father distrusted the public school system. She began formal art lessons with her father at age 11, making charcoal studies and geometric shapes.

A child prodigy,^[7] at age 13 Wyeth was enrolled in the Normal Arts School in Boston, Massachusetts. The next year, in 1921, she entered the Boston Museum of Art Academy. Two years later she moved to Philadelphia to study painting at the Pennsylvania Academy of Fine Arts.^[2] By age 16, she was well known as a portraitist and received commissions for paintings of Wilmington residents. Deeply influenced by her father's unique realistic style, she rejected early 20th-century painting styles such as Impressionism and Cubism. She was also socially and politically conservative. As a result, later in life she rejected the progressive movements of the 1960s and 1970s, including the women's movement. She often criticized television and modern culture.^[7]

Soon after her student years, Hurd exhibited at the Pennsylvania Academy (1927, 1936–44), where she was awarded the 1937 Mary Smith Prize for a portrait of her son Peter.^[8] Wyeth's work spanned portraits of adults and children, still lifes, and floral landscapes. In her work, she "often included objects that related to the subject's interest or personality".^[9] She eventually stopped painting children because, as she said, "today's children--they are so deadpan."^[7]

She painted for Helen Hayes, Paulette Goddard, and Mrs. John D. Rockefeler III (Blanchette Hooker Rockefeler), for which she earned a lasting celebrity.^[7] In 1963, she painted a portrait of her brother Andrew for the cover of Time magazine. Hurd and Wyeth were both commissioned to produce a cover portrait of President Lyndon B. Johnson for Time's "Man of the Year" issue. She received awards for her work, including the Governor's Award in New Mexico^[2] and a Living Legacy Award from the Women's International Center.^[1]

Her most widely known work is the official White House portrait of First Lady Pat Nixon.^[10]

At age 21, in 1929 Wyeth married artist Peter Hurd, a fellow student at the Pennsylvania Academy and her father's apprentice. The couple had three children together: Peter Jr., Carolyn, and Michael Hurd. In the mid-1930s they moved to San Patricio, New Mexico, settling on a farm of 40 acres. By 1939, they established the Sentinel Ranch there, gradually acquiring more land until they had 2200 acres. It was in southern New Mexico near Roswell, New Mexico, her husband's birthplace.^[5]

Wyeth's father was not happy when they left the Pennsylvania area. As she said in a 1989 interview, "He felt I should not let marriage interfere with my painting" and worried that living on a ranch would draw her energy from it. Henriette Wyeth, however, did continue to paint for the rest of her life and was inspired by the landscape. Later health problems prevented her from making art.^[7] She criticized contemporary television and feminism, and said that modern society had "blunted" children.

Henriette Wyeth died in her Roswell, New Mexico home-studio from complications from pneumonia in April 1997.^[7]

According to her biography on the Wyeth Hurd Gallery website, she was "considered by many art scholars to be one of the great women painters of the 20th century".^[11] Her papers, and those of her husband (who died in 1984), are in the Archives of American Art at the Smithsonian Institution.

Much of her work is held by the Roswell Museum and Art Center, in Roswell^[10] and at the Hurd La Rinconada Gallery in San Patricio, both in New Mexico. Her paintings can also be found in the permanent collections of the Brandywine River Museum in Pennsylvania, the Los Angeles Athletic Club, the National Portrait Gallery, the New Mexico Museum of Art in Santa Fe, and the Texas Tech University Fine Art Museum.^[12] Wyeth's work has also been exhibited at such notable institution as the Metropolitan Museum of Art in New York, the Carnegie Institute in Pittsburgh, the Art Institute of Chicago and New Mexico's Roswell Museum of Art.^[7]

Other exhibitions have included:

• The Wyeth Family (1935), Philadelphia, Pennsylvania^[13]
• Exhibition of Paintings by Peter Hurd & Henriette Wyeth (1967), the Columbus Gallery of Fine Arts, Columbus, Ohio^[14]

Her work has also been included in a number of posthumous exhibitions:

• The Wyeths' Wyeths (2010), Farnsworth Art Museum, Rockland, Maine
• The Wyeth Family: Three Generations of American Art (2010), Dulwich Picture Gallery, London^[15]
• The Wyeths: America's Artists (2011), Kalamazoo Institute of the Arts, Kalamazoo, Michigan^[16]
• Nomads: Traversing Adolescence (2013), Kemper Museum of Contemporary Art, Kansas City, Kansas, and Kemper East, Kansas City, Missouri^[15]
• Magical & Real: Henriette Wyeth and Peter Hurd, a Retrospective (2018), Michener Art Museum, Doylestown, Pennsylvania^[17]

• Wyeth

• Henriette Wyeth, from Ask Art.
• Peter Hurd and Henriette Wyeth Hurd papers, 1917–1989, Archives of American Art, Smithsonian Institution.
• Biography, from the Women's International Center.
• Obituary: "Henriette Wyeth, 89, A Portrait Painter In a Family of Artists", The New York Times, April 6, 1997.