Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.[3][4][5]
KRT85 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | KRT85, ECTD4, HB5, Hb-5, K85, KRTHB5, hHb5, keratin 85 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602767 HomoloGene: 37603 GeneCards: KRT85 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.[5]
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