MRGPRX3 Knowpia

MRGPRX3
Identifiers
Aliases	MRGPRX3, GPCR, MRGX3, SNSR1, SNSR2, MAS related GPR family member X3
External IDs	OMIM: 607229 MGI: 3033148 HomoloGene: 79615 GeneCards: MRGPRX3
Gene location (Human)
Chr.	Chromosome 11 (human)
End	18,138,488 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	46,902,596 bp
RNA expression pattern
	Top expressed in
	minor salivary glands; ; urinary bladder; ; vagina; ; smooth muscle tissue; ; tibial nerve;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane; integral component of plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	117195
	668725
	ENSG00000179826
	ENSMUSG00000074111
	Q96LB0
	n/a
	NM_054031; NM_001370464
	NM_001177566; NM_001288801
	NP_473372; NP_001357393
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Mas-related G-protein coupled receptor member X3 is a protein that in humans is encoded by the MRGPRX3 gene.^[5]^[6]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000179826 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000074111 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell. 106 (5): 619–32. doi:10.1016/S0092-8674(01)00483-4. PMID 11551509. S2CID 14119088.
^ "Entrez Gene: MRGPRX3 MAS-related GPR, member X3".

Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634. S2CID 42544746.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kaisho Y, Watanabe T, Nakata M, et al. (2005). "Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype". Biochem. Biophys. Res. Commun. 330 (3): 653–7. doi:10.1016/j.bbrc.2005.03.027. PMID 15809047.