OR4A47

Summary

Olfactory receptor 4A47 is a protein that in humans is encoded by the OR4A47 gene.[5]

OR4A47
Identifiers
AliasesOR4A47, OR11-113, olfactory receptor family 4 subfamily A member 47
External IDsMGI: 3031090 HomoloGene: 128157 GeneCards: OR4A47
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001005512

NM_146983

RefSeq (protein)

NP_001005512

NP_667194

Location (UCSC)Chr 11: 48.49 – 48.49 MbChr 2: 89.66 – 89.67 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000237388 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075073 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR4A47 olfactory receptor, family 4, subfamily A, member 47".

Further reading edit

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi:10.1038/nature04632. PMID 16554811.

External links edit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.