OR52A1 Knowpia

OR52A1
Identifiers
Aliases	OR52A1, HPFH1OR, olfactory receptor family 52 subfamily A member 1
External IDs	MGI: 1341790 HomoloGene: 130658 GeneCards: OR52A1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	5,154,757 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	103,428,905 bp
RNA expression pattern
	Top expressed in
	organ system; ; material anatomical entity; ; blood; ; multicellular organism;
	Top expressed in
	supraoptic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	23538
	18369
	ENSG00000182070
	ENSMUSG00000061626
	Q9UKL2
	E9PYY2
	NM_012375
	NM_013620
	NP_036507
	NP_038648
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 52A1 is a protein that in humans is encoded by the OR52A1 gene.^[5]^[6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[6]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182070 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061626 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Feingold EA, Penny LA, Nienhuis AW, Forget BG (Nov 1999). "An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells". Genomics. 61 (1): 15–23. doi:10.1006/geno.1999.5935. PMID 10512676.
^ ^a ^b "Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1".