Retinyl acetate (retinol acetate, vitamin A acetate) is a natural[dubious ] form of vitamin A which is the acetate ester of retinol. It has potential antineoplastic and chemopreventive activities.[2][3]
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IUPAC name
(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
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Other names
Retinol acetate; Vitamin A acetate; Vitamin A1 acetate; Acetylretinol; all-trans-Retinol acetate; all-trans-Retinyl acetate; all-trans-Vitamin A acetate;
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3D model (JSmol)
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1915439 | |
ChEBI |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.004.405 |
EC Number |
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KEGG |
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PubChem CID
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UNII |
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CompTox Dashboard (EPA)
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Properties | |
C22H32O2 | |
Molar mass | 328.496 g·mol−1 |
Melting point | 57 to 58 °C (135 to 136 °F; 330 to 331 K)[1] |
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H315, H361, H413 | |
P201, P202, P264, P273, P280, P281, P302+P352, P308+P313, P321, P332+P313, P362, P405, P501 | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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In the United States, retinyl acetate is classified generally recognized as safe (GRAS) in the amounts used to fortify foods with vitamin A.[4][5]
World Health Organization "Recommendations for preformed vitamin A supplements for mothers during pregnancy" states that "health benefits are expected for the mother and her developing fetus with little risk of detriment to either, from a daily supplement not exceeding 10,000 IU vitamin A (3000mcg RE) at any time during pregnancy." Preformed Vitamin A refers to retinol and retinyl esters, such as retinyl palmitate and retinyl acetate.[6]