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SERPINB8

Summary

Serpin B8 is a protein that in humans is encoded by the SERPINB8 gene.[5][6][7]

SERPINB8
Identifiers
AliasesSERPINB8, CAP2, PI8, serpin family B member 8, PSS5, PI-8, HMSD, HSMD-v, C18orf53
External IDsOMIM: 601697 MGI: 894657 HomoloGene: 74445 GeneCards: SERPINB8
Orthologs
SpeciesHumanMouse
Entrez

5271

20725

Ensembl

ENSG00000166401

ENSMUSG00000026315

UniProt

P50452

O08800

RefSeq (mRNA)

NM_001159748
NM_011459

RefSeq (protein)

NP_001153220
NP_035589

Location (UCSC)Chr 18: 63.97 – 64.02 MbChr 1: 107.52 – 107.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166401 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026315 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem. 270 (50): 29854–61. doi:10.1074/jbc.270.50.29854. PMID 8530382.
  6. ^ Bartuski AJ, Kamachi Y, Schick C, Overhauser J, Silverman GA (Nov 1997). "Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3". Genomics. 43 (3): 321–8. doi:10.1006/geno.1997.4827. PMID 9268635.
  7. ^ "Entrez Gene: SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8".

Further reading edit

  • Hubberstey A, Yu G, Loewith R, et al. (1997). "Mammalian CAP interacts with CAP, CAP2, and actin". J. Cell. Biochem. 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950. S2CID 46076387.
  • Dahlen JR, Foster DC, Kisiel W (1998). "Expression, purification, and inhibitory properties of human proteinase inhibitor". Biochemistry. 36 (48): 14874–82. doi:10.1021/bi970977p. PMID 9402754.
  • Reddy PH, Stockburger E, Gillevet P, Tagle DA (1998). "Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method". Genomics. 46 (2): 174–82. doi:10.1006/geno.1997.5044. PMID 9417904.
  • Dahlen JR, Jean F, Thomas G, et al. (1998). "Inhibition of soluble recombinant furin by human proteinase inhibitor 8". J. Biol. Chem. 273 (4): 1851–4. doi:10.1074/jbc.273.4.1851. PMID 9442015.
  • Strik MC, Bladergroen BA, Wouters D, et al. (2003). "Distribution of the human intracellular serpin protease inhibitor 8 in human tissues". J. Histochem. Cytochem. 50 (11): 1443–54. doi:10.1177/002215540205001103. PMID 12417609.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hoetelmans RW (2004). "Nuclear partners of Bcl-2: Bax and PML". DNA Cell Biol. 23 (6): 351–4. doi:10.1089/104454904323145236. PMID 15231068.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Leblond J, Laprise MH, Gaudreau S, et al. (2006). "The serpin proteinase inhibitor 8: an endogenous furin inhibitor released from human platelets". Thromb. Haemost. 95 (2): 243–52. doi:10.1160/TH05-08-0561. PMID 16493485. S2CID 3620828.

External links edit

  • The MEROPS online database for peptidases and their inhibitors: I04.013
  • SERPINB8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)