Sulfalene (INN, USAN) or sulfametopyrazine (BAN) is a long-acting sulfonamide antibacterial used for the treatment of chronic bronchitis, urinary tract infections and malaria.[2][3] As of 2014 there were only two countries in which it is currently still marketed: Thailand and Ireland.[3]
Clinical data | |
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Trade names | Eadazine, Kelfizina, Kelfizine W, Longum |
Other names | Sulfametopyrazine |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral[1] |
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Pharmacokinetic data | |
Protein binding | 60 to 80%[1] |
Elimination half-life | 60 to 65 hours[1] |
Excretion | Urinary[1] |
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ECHA InfoCard | 100.005.278 |
Chemical and physical data | |
Formula | C11H12N4O3S |
Molar mass | 280.30 g·mol−1 |
3D model (JSmol) |
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It was discovered by researchers at Farmitalia and first published in 1960 and was marketed as Kelfizina.[4][5]