OR2J2 Knowpia

OR2J2
Identifiers
Aliases	OR2J2, OR6-19, OR6-8, OR6.3.8, ORL684, dJ80I19.4, hs6M1-6, olfactory receptor family 2 subfamily J member 2
External IDs	HomoloGene: 88922 GeneCards: OR2J2
Gene location (Human)
Chr.	Chromosome 6 (human)
End	29,175,811 bp
RNA expression pattern
	Top expressed in
	uterine tube; ; testicle; ; appendix; ; hippocampus proper; ; hypothalamus; ; caudate nucleus;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26707
	n/a
	ENSG00000204700
	n/a
	O76002
	n/a
	NM_030905
	n/a
	NP_112167
	n/a
	Wikidata
View/Edit Human

Olfactory receptor 2J2 is a protein that in humans is encoded by the OR2J2 gene.^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[3]

Ligands edit

Agonists include:^[4]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000204700 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR2J2 olfactory receptor, family 2, subfamily J, member 2".
^ Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009). "Odor coding by a Mammalian receptor repertoire". Science Signaling. 2 (60): ra9. doi:10.1126/scisignal.2000016. PMC 2774247. PMID 19261596.