Synthetic Lysosomal
Enzymes Market: Introduction
·
Lysosomal enzymes are enzymes or catalysts that naturally occur
in the body and help in performing different metabolic processes
·
Lysosomal enzymes help break down large molecules and other
ingredients that are taken up by cells to perform different functions of the
body. The nuclear gene controls the synthesis of lysosomal enzymes.
·
Deficit of lysosomal enzymes due to genetic mutation causes complications
such as storage disease, which can affect growth and development of an organ
and lead to organ failure
·
The last two decades witnessed increase in research &
development in the field of artificial genetic material. There have been
advancements in the treatment of lysosomal storage disorder due to development
of various therapeutic approaches such as enzyme replacement therapy and
development of synthetic enzymes.
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Key Drivers and
Restraints of Global Synthetic Lysosomal Enzymes Market
·
Rise in prevalence of lysosomal enzyme related diseases such as lysosomal
storage diseases is projected to drive the global synthetic lysosomal enzymes
market during the forecast period
·
According to the National Institutes of Health Genetics Home
Reference, Fabry disease affects an estimated 1 in 40,000 to 60,000 males
globally. According to the National Center for Biotechnology Information
(NCBI), in January 2020, the prevalence of Fabry disease in white male
populations was 1:17,000 to 1:117,000 in the U.S. Rise in prevalence of Fabry
disease is anticipated to drive the global synthetic lysosomal enzymes market.
·
Increase in geriatric population, which is more likely to suffer
from Duchenne muscular dystrophy, is one of the major factors propelling the
global synthetic lysosomal enzymes market
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·
According to the World Health Organization (WHO), population
aged 60 years and above is projected to rise from 900 million in 2015 to 2
billion in 2050. Increase in the geriatric population leads to surge in
incidence of Duchenne muscular dystrophy and other lysosome related diseases.
This is expected to boost the growth of the global synthetic lysosomal enzymes
market.
·
Moreover, high prevalence of thrombocytopenia disorder is likely
to drive the global market during the forecast period
·
However, side effects associated with synthetic enzymes such as
breathing problems, swelling of the lips, and itching are expected to hamper
the growth of the global market in the next few years
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North America to Lead
Global Synthetic Lysosomal Enzymes Market
·
In terms of region, the global synthetic lysosomal enzymes
market can be segmented into North America, Europe, Asia Pacific, Latin
America, and Middle East & Africa
·
North America dominated the global market in 2020. The region is
projected to account for significant share of the global market during the
forecast period, due to rise in the prevalence of metabolic muscular disorders.
·
Europe was the second largest market for synthetic lysosomal
enzymes in 2020. Increase in the geriatric population and rise in prevalence of
Gaucher’s disease are anticipated to drive the market in the region during the
forecast period.
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·
The market in Asia Pacific is expected to expand at a faster
CAGR during the forecast period due to rise in prevalence of muscular dystrophy
disorder. Moreover, awareness about the effects of lysosomal storage disorders
in countries such as India, China, the Philippines, and Singapore are likely to
drive the market in Asia Pacific during the forecast period.
·
Latin America is projected to be a lucrative market for
synthetic lysosomal enzymes during the forecast period due to rise in health
awareness among people
·
Increase in awareness about the harmful effects of lysosomal
storage disorders and high diagnosis rates are anticipated to augment the
synthetic lysosomal enzymes market in Middle East & Africa during the
forecast period.
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