Have heard a lot of Viagra and its properties of treating erectile dysfunction in men and want to know what the hype is all about? Well, you have to the right place looking for your answer. Viagra is a global standard oral medication recommended and prescribed by doctors around the world to people who have mild to severe erectile dysfunction. It was first manufactured by Pfizer for the treatment of pulmonary hypertension and then later used to treat erectile dysfunction. In this article, we will tell you how does Viagra actually works and what is the key component in it that is responsible for the caused erections. Keep on reading to learn and understand the working process of Viagra tablets.
Viagra was first manufactured by Pfizer for the treatment of chest pain caused by pulmonary arterial hypertension. However, Viagra was later found to promote healthy and strong erections in men. Pfizer's patent right expired in 2007 and since then many pharmaceutical companies have been manufacturing their own generic form.
Erectile dysfunction is a common sexual problem that men experience due to aging and various other factors. Erectile dysfunction is medically characterized as a condition where one is unable to get or hold an erection firm enough for intercourse. A number of psychological and physical factors can cause it. Psychological factors include stress, anxiety, and hypertension. Physical factors such as cardiovascular diseases, high blood cholesterol levels, and type 2 diabetes can also cause erectile dysfunction in men. Other causes include excessive smoking, drug use, and alcohol addiction. Some antidepressants medications can also cause erectile dysfunction in men as a side effect. Erectile dysfunction basically is caused due to improper blood supply to the penile region. The insufficient blood supply in the penile region hampers the ability to get a firm erection strong enough to perform sexual activity therefore, one suffers from the problem of erectile dysfunction. Erectile dysfunction can affect your relationship with your partner and create a distance. The overall relationship with your partner can be affected due to erectile dysfunction and you might feel quite distant from each other.
Sildenafil Citrate: The Key Component
Sildenafil Citrate is the main component in Viagra pills. It works by preventing the action of (PDE-5) phosphodiesterase type-5. The release of nitric oxide smooths the muscles and widens the blood vessels. This smooth relaxation of widened blood vessels and encourages more blood supply to the penile region, thereby providing a hard-on to have pleasurable sex. The important thing to note here is to consume the pill 30-40 minutes prior to the lovemaking session and it only works when the body experiences complete arousal.The Role of Pde-5 Inhibitors Like Sildenafil Citrate in the Treatment of Erectile Dysfunction
During a normal penis erection, parasympathetic stimulation in the penis leads to nitric oxide released from cells within the penis. After sexual stimulation, the released nitric oxide concentration is significantly increased and this increment contributes to the conversion of guanosine triphosphate to cyclic guanosine monophosphate (cGMP). Downstream of cGMP decreases calcium ions in the newly formed cavernosal smooth muscles, leading to smooth muscle relaxation of the penis muscles. Once relaxed, these smooth muscles collapse the veins, which causes reduced drainage of arterial blood, thereby leading to an erection. But there can be many causes that affect this process leading to the inability to gain an erection. These causes are which lead to erectile dysfunction in men.Comprehension of the subtle differences between the PDE5 inhibitors will help the healthcare professional select the appropriate method that meets your needs and causes less to no damage with heightened effectiveness. This is how Sildenafil Citrate helps as a PDE-5 inhibitor in the treatment process of erectile dysfunction in men.
