Bone
Regeneration Material Market: Introduction
Bone-regeneration
techniques, either with autografts or allografts, represent a challenge for
reconstructive surgery. Biomaterials are temporary matrices for bone growth and
provide a specific environment and architecture for tissue development.
Depending on the specific intended application of the matrix, whether for
structural support, drug-delivery capability, or both, certain material
categories may be more or less well suited to the final structure.
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Key
Drivers and Restraints of Global Bone Regeneration Material Market
·
Increase in prevalence of degenerative
joint diseases boost the market. Worldwide estimates of degenerative joint
diseases indicate that 9.6% men and 18.0% women above 60 years have symptomatic
osteoarthritis. According to expert opinions presented in the EULAR committee
report, radiographic evidence of knee osteoarthritis in men and women over 65
years of age is found in 30% of the population. In the absence of disease
modifying therapy, a large number of patients with osteoarthritis progress to
advance joint destruction. Surgery with bone grafts and substitutes play a
major role in the management of osteoarthritis to avoid advanced joint
destruction. According to the American College of Rheumatology, advances in
biomaterial and tissue engineering are expected to create new opportunities to
integrate surgical approaches in osteoarthritis.
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·
Increase in the number of orthopedic
surgeries also fuels the market. According to the American Academy of
Orthopaedic Surgeons (AAOS), approximately 129,000 total knee arthroplasty
(TKA) surgeries were performed in the U.S. in 1990, and the number has
increased to over 600,000 in 2010. The AAOS has projected that 3 million TKA
procedures would be performed by 2030 in the U.S. alone. Moreover, spinal
surgeries are becoming increasingly popular, and approximately 432,000 spinal
fusions are performed in the U.S. each year. Bone grafts and substitutes are
extensively used for the surgeries mentioned above. This is likely to fuel the
bone regeneration material market.
·
Bone graft and substitutes are a long-term
solution to bone problem treatment; however, these are expensive. No two
patients or their customized bone grafts and substitutes treatments are exactly
alike. Hence, the number of appointments, procedures, and costs vary accordingly.
Surgeons charge US$ 35,000 to US$ 40,000 for a complex posterolateral lumbar
spine fusion bone graft surgery. Most surgeons refer patients to specialty
surgeons, neurologists, or orthopedic physicians, which increases the cost of
procedure. Asia is price-sensitive and displays inhibitions with respect to
investing in bone graft and substitutes, which are often only affordable to the
elite population; therefore offering a comparatively smaller market
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Cell-based Segment to Expand Significantly
·
Based on product type, the global bone
regeneration material market can be divided into ceramic-based, polymer-based,
growth factor-based, cell-based and others
·
The ceramic-based segment dominated the
global market in 2019. It is projected to sustain its position during the
forecast period. Ceramic-based bone grafts are widely used to reduce the need
for iliac crest bone grafting. Rise in geriatric population with oral health
issues across the world has augmented the number of bone graft surgeries
performed in the last few years.
·
However, the cell based segment is
projected to expand at a notable CAGR during the forecast period. Bone tissue
engineering (BTE) using bone marrow stem cells has been suggested as a
promising technique for reconstructing bone defect in order to overcome the
drawbacks of bone graft materials.
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Orthopedic
surgery segment to dominate global bone regeneration material market
·
Based on application, the global bone
regeneration material market can be segregated into orthopedic surgery, bone
trauma, dental surgery and others.
·
In terms of revenue, the orthopedic surgery
segment accounted for a prominent share of the market in 2019 owing to a rise
in the geriatric population and increase in cases of orthopedic diseases.
According to WHO, between 2015 and 2050, the proportion of the world's
population over 60 years would nearly double from 12% to 22%. The number of
people aged 60 years and older is estimated to outnumber children younger than
5 years by 2020. As per MVZ Gelenk-Klinik data, more than 2400 orthopedic
surgical procedures are performed per year at the Gelenk Klinik Orthopaedic
Hospital.
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North
America to dominate global bone regeneration material market
·
In terms of region, the global bone
regeneration material market can be divided into: North America, Europe, Asia
Pacific, Latin America, and Middle East & Africa
·
North America accounted for a significant
share of the bone regeneration material market in 2019, followed by Europe.
Usage of new and innovative products in both premium and value segments among
various bone grafts substitutes is projected to boost the bone regeneration
material market in several countries in Europe and North America in the next
few years. According to the Centers for Disease Control and Prevention (CDC),
the total number of inpatient surgeries carried out in the U.S. were 51.4
million in 2014; of these 719,000 were total knee replacements and 332,000 were
total hip replacement.
·
The market in developing countries in Asia
Pacific is estimated to expand at a significant CAGR during the forecast
period. The market in Asia Pacific is driven by an increase in population and
time taken to accept new technologies. Increase in the number of patients and
geriatric population are major factors that are expected to propel the market in
Japan during the forecast period. According to the Gerontological Society of
America, Japan has the highest proportion of geriatric population in the world.
Hence, demand for orthopedic surgeries is estimated to be higher in Japan than
that in other countries in Asia Pacific.
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