Global
Hereditary Cancer Testing Market: Overview
·
Hereditary cancers are caused by gene mutations that
people are born with; passed down to them from either their mother or their
father. According to many medical research report, between 5% and 10% of many
common cancers are considered hereditary.
·
Genetic testing is done to determine whether someone
carries a harmful variant of genes and it also help to determine whether family
members who have not yet developed a cancer have inherited the same variant as
a family member who is known to carry a harmful (cancer susceptibility
predisposing) variant.
·
Different types of gene mutations are responsible for
different cancers. For instance, BRCA1 and BRCA2 are the two genes most
commonly responsible for hereditary breast and ovarian cancer.
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Key
Drivers of Global Hereditary Cancer Testing Market
·
Breast cancer is one of the most common cancers in the
world affecting almost 12.5% of women during their lifetime and 5%–10% of these
patients have a hereditary form. BRCA1 and BRCA2 genes are the most commonly
mutated genes, but additional genes associated with hereditary breast cancer
are emerging. New advances in genomic technologies have led to parallel testing
of multiple genes. Customized next generation sequencing panels are now
providing the simultaneous analysis of breast cancer predisposition genes, from
high to intermediate penetrant genes. This development in genomic technology is
likely to drive the market.
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Restraints
of Global Hereditary Cancer Testing Market
·
The implementation of hereditary multigene panel testing
arises many issues, such as which are the criteria that patients have to meet
in order to undergo the test and the patient’s clinical management. The
utilization of the test must be in compliance with the recommendations for
genetic testing identified in the (American Society of Clinical Oncology, Inc.)
ASCO policy. This can limit the number of tests.
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North
America to Account for Major Share of Global Hereditary Cancer Testing Market
·
Rapid expansion of the test due to high awareness, high
incident rate of cancer specially breast cancer, and favorable reimbursement
policies are expected to drive the market in North America. Many research
studies estimate that more than 276,000 new cases of invasive breast cancer are
likely to be diagnosed in U.S. women in 2020.
·
Male breast cancer represents less than 1% of all breast
cancer diagnoses. Data from research study states that about 2,600 new cases of
breast cancer are expected to be diagnosed in men in 2020.
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