Wolfram
Syndrome Treatment Market: Introduction
·
Wolfram syndrome is an inherited condition
characterized by the childhood onset of diabetes mellitus, diabetes insipidus,
and optic atrophy, causing gradual loss of vision and deafness
·
Wolfram syndrome is a rare
neurodegenerative disease that is considered as a prototype of the endoplasmic
reticulum disease. There are two identified causative agents, WFS1 and WFS2,
responsible for Wolfram syndrome.
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·
Other major symptoms of Wolfram syndrome
are bowel & bladder dysfunction, causing vestibular deficits, temperature regulation
problems, olfactory defects, and decreased balance. As per research published
by National Institute of Health (NIH), 65% of the people suffering from Wolfram
syndrome suffer from sensorineural deafness and 70% of Wolfram syndrome
patients are expected to suffer from diabetes insipidus condition.
·
Moreover, 60% to 90% of Wolfram syndrome
patients are likely to suffer with urinary tract condition. About 60% of
Wolfram syndrome patients are likely to develop neurological disorder. Several
patients suffering from Wolfram syndrome are expected to develop
insulin-dependent diabetes mellitus before the age of 16, which accounted for
87% of the total patient population.
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Key
Drivers, Restraints, and Opportunities of Wolfram Syndrome Treatment Market
·
Rise in awareness about Wolfram syndrome
and standard diagnosis rate of Wolfram syndrome, increasing incidences of the
diabetes mellitus are a few factors that are anticipated to propel the market
globally
·
Clinical trials are underway to investigate
differentiation in type 1 and type 2 wolfram syndrome to diagnosis and
prognosis of the disease for different patient population. Investments in
research & development to identify the treatment of the syndrome is also
estimated to propel the market globally.
·
Wolfram syndrome affects around 1 in
200,000 to 500,000 people across globe and as per medical experts, around
15,000 to 30,000 patients are estimated to be suffering from Wolfram syndrome.
In the U.S., Wolfram syndrome was likely to have affected between 1,000 and
2,000 people in 2019. These statistics indicate that patients suffering from
Wolfram syndrome die before the age of 40.
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North
America to Dominate Global Wolfram Syndrome Treatment Market
·
North America is anticipated to account for
a notable share of the market during the forecast period, followed by Europe.
Rise in number of people suffering from diabetes mellitus in the U.S. drives
the attention toward diagnosis of Wolfram syndrome. Increase in diagnosis and
research for development for the treatment of Wolfram syndrome disease is another
major factor propelling the market in the region. In North America, wolfram
syndrome affects around 1 in 100,000 population.
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·
In Europe, the incidence of Wolfram
syndrome is increasing and is recognized as a rare disease in the region.
Prevalence of Wolfram syndrome is affecting around 5 per 10,000 population in
the region. In the U.K., the prevalence of Wolfram syndrome was estimated to be
1 in 770,000 in 2018.
·
Technological advancements, standard
diagnostic tools for detection of the rare diseases, rising awareness, and
accessibility to healthcare infrastructure are a few factors that are estimated
to fuel the Wolfram syndrome treatment market during the forecast period.
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