Microdialysis:
Introduction
·
The microdialysis technique is an
expensive, invasive, and a new real-time continuous in vivo sampling technique
·
Microdialysis is
a minimally invasive sampling method that is used for continuous measurement of
unbound, free analyte concentrations in the extracellular fluid of any tissue
·
Analytes may include exogenous compounds to
determine their distribution within the body or endogenous molecules to measure
their biochemical functions in the body
·
This method requires the insertion of a
small microdialysis probe or catheter into the tissue of interest
·
The technique was first applied in the
early 1960s. Microdialysis techniques are extensively employed for sampling
extracellular fluid in living organs. The first target for application of
microdialysis technique was the central nervous system (CNS) of experimental
animals.
·
The microdialysis technique has been used
to study brain neurophysiology and the release of metabolites,
neurotransmitters, amino acids, monoamines, and other small endogenous
compounds.
·
It is a valuable tool for in vivo
evaluation studies on drug metabolism, bioavailability, bioequivalence, and
pharmacodynamics and pharmacokinetics, drug delivery, and pharmacological
efficacy
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Key
Drivers of Global Microdialysis Market
·
Increase in the usage of microdialysis
technique in diverse applications is expected to drive the microdialysis market
during the forecast period
·
The technique is being utilized to monitor
concentration of both exogenous and endogenous biomolecules in a range of
tissue types such as reproductive organs, liver, blood, muscles, eyes, lungs,
adipose tissues, and skin
·
The microdialysis technique is also gaining
popularity in the pharmacokinetic and pharmacodynamics (PK/PD) studies both in
animals and humans is expected to drive the market during the forecast period
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Clinical
to be Highly Attractive Segment of Global Microdialysis Market
·
In terms of application, the global
microdialysis market can be classified into research and clinical
·
The clinical segment is projected to expand
at a rapid pace during the forecast period. Rise in adoption of microdialysis
in human clinical trials is a major factor that is estimated to drive the
clinical segment during the forecast period.
·
Increase in usage of microdialysis
technique for various research applications in central nervous system is likely
to drive the research segment during the forecast period
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North America to Dominate the Global
Microdialysis Market
·
In terms of region, the global microdialysis
market can be segmented into North America, Europe, Asia Pacific, Latin
America, and Middle East & Africa. North America is projected to dominate
the global microdialysis market during the forecast period.
·
New product launches, presence of favorable
insurance coverage, technological advancements in microdialysis techniques,
increasing focus on skin microdialysis, growing interest in online
microdialysis-based analytical systems, and rising prevalence of chronic
diseases in the region are expected to drive the microdialysis market in the
region during the forecast period.
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Key
Players Operating in Global Microdialysis Market
The global
microdialysis market is concentrated with the presence of international and few
local players.
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