Parenteral
Medication of Spasticity Treatment: Introduction
·
Spasticity is a condition in which
muscles stiffen or tighten, preventing normal fluid movement. The muscles
remain contracted and resist being stretched, thus affecting movement, speech,
and gait.
·
Spasticity is generally caused by damage or
disruption to the areas of the brain and spinal cord that are responsible for
controlling muscle and stretch reflexes. These disruptions can be due to an
imbalance in the inhibitory and excitatory signals sent to the muscles, causing
them to lock in place.
·
Parenteral treatment for spasticity
includes botulinum toxin injection and phenol/alcohol injection. More effective
methods of treatment for spasticity have still not been well-developed.
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Key
Drivers of Global Parenteral Medication of Spasticity Treatment Market
·
Increase in number of patients of
spasticity associated with multiple sclerosis and spinal cord injury is
anticipated to fuel the demand for therapeutics and consequently, drive the
spasticity treatment market during the forecast period. According The National
Center for Biotechnology Information, spasticity affects more than 12 million
people worldwide. More than 500,000 people in the U.S. are estimated to suffer
from upper limb spasticity.
·
According to National Multiple Sclerosis
Society, nearly 1 million people in the U.S. are living with multiple
sclerosis, and spasticity occurs in up to 84% of multiple sclerosis patients.
·
Data suggest that about 65% to 78% of the
SCI population have some amount of spasticity, and it is more common in
cervical (neck) than thoracic (chest) and lumbar (lower back) injuries
·
Ongoing clinical trials for spasticity
treatment, drugs, pipeline products, and safety and efficacy studies have
increased in the last few years. For instance, Revance Therapeutics, Inc. has
an innovative product, i.e. Daxibotulinumtoxin A, for Injection in phase II for
the treatment of upper limb spasticity.
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Botulinum
Toxin Injection Segment to be Highly Promising
·
Based on product type, the global
parenteral medication of spasticity treatment market can be segmented into
botulinum toxin injection and phenol/alcohol injection. The botulinum toxin
injection segment can be further classified into Botox, Myobloc, Dysport, and
others.
·
The botulinum toxin injection segment accounted
for a prominent share of the global parenteral medication of spasticity
treatment market in 2019. This segment is expected to dominate the parenteral
medication of spasticity treatment market due to an increase in use of Botox,
Myobloc, and Dysport in the treatment of spasticity.
·
Botulinum toxin products, such as Botox,
are known to create an 88% improvement in stance, 77% improved gait speed, 88%
improved joint positions. Additionally, strong botulinum toxin product pipeline
is likely to drive the segment during the forecast period.
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Hospital
Pharmacies to be Most Promising Segment
·
In terms of distribution channel, the
global parenteral medication of spasticity treatment market can be divided into
hospital pharmacies, retail pharmacies, and online pharmacies. Hospital
pharmacies was a prominent segment, in terms of revenue, in 2019. It is
anticipated to expand significantly during the forecast period.
·
Expansion of healthcare infrastructure and
increase in availability of all treatment options at one place are anticipated
to boost the hospital pharmacies segment
·
Increase in number of patients with
spasticity associated multiple sclerosis and spinal cord injury who require
hospital visits fuels the hospital pharmacies segment
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North
America to Dominate Global Parenteral Medication of Spasticity Treatment Market
·
In terms of region, the global parenteral
medication of spasticity treatment market can be categorized into North
America, Europe, Asia Pacific, Latin America, and Middle East & Africa
·
North America dominated the global
parenteral medication of spasticity treatment market in 2019. It is expected to
maintain its leading position during the forecast period. Dominance of the
region can be attributed to an increase in patients with multiple sclerosis and
spinal cord injury. Spasticity is commonly witnessed in multiple sclerosis and
spinal cord injury patients. According to National Spinal Cord Injury
Statistical Center, around 288,000 persons suffer from spinal cord injury, this
range varies from 247,000 to 358,000 persons.
·
The market in Asia Pacific is projected to
expand at a significantly high growth rate during the forecast period, owing to
an increase in prevalence of multiple sclerosis and spinal cord injury, and
strokes in emerging countries such as India and China
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Key
Manufacturers Operating in Global Market
The global
parenteral medication of spasticity treatment market was highly fragmented in
2019.
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