Epistaxis is a condition that results in uncertain
nose bleeding from either of the nostrils. This clinical condition is usually
classified as anterior epistaxis and posterior epistaxis based on the site
where the bleeding originates. Epistaxis is rarely life threatening unless it
is associated with chronic disorders such as cancer. About 10% of nosebleeds is
life threatening, and it is accounted that four of the 2.4 million deaths occur
due to epistaxis. This condition commonly occurs in younger children (2-10
years) and older people (50-80 years); however, it is more common among
individuals who are above 50 years of age. Prevalence is higher in males (58%)
as compared to females (42%). It is usually caused by local trauma, including
nasal infection and even nose picking. Environmental factors causing epistaxis
include dry climate, lack of humidity in the atmosphere, or prolong inhalation
of dry air. People who are on medications such as warfarin, clopidogrel,
aspirin, or any other anticoagulant medications are more susceptible to
epistaxis. Other predisposing factors such as infection, allergic and
non-allergic rhinitis, cocaine snorting, hypertension, alcohol abuse, and
inherited bleeding problems also lead to epistaxis.
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In terms of treatment, the global epistaxis market
is segmented as topical vasoconstrictors, antibiotic ointments (mupirocin),
anesthetics, and nasal cautery. The topical vasoconstrictors segment includes
oxymetazoline, co-phenylcaine, or adrenaline, which are applied directly to the
mucous membrane. The anesthetics segment includes lidocaine or lignocaine and
is often given in combination with vasoconstrictors. Nasal cautery is the most
common treatment of epistaxis. Chemical cautery (silver nitrate) and
electrocautery (an electrically charged wire such as platinum) are two types of
nasal cautery. Chemical cautery is the most popular method for the treatment of
idiopathic recurrent epistaxis. Most of the research is focused on device
development, thus boosting the growth of the epistaxis market. In 2016, Smith
& Nephew launched a range of epistaxis management devices using ‘rapid
rhino technology’ that has a blend of carboxymethyl cellulose (CMC), which
exhibit self-lubricating properties that provide gentle and even compression to
the nasal area and helps in the quicker re-conformation of the nasal anatomy.
Additionally, growing incidence rates of epistaxis and chronic diseases boost
the growth of the global epistaxis market. The lifelong incidence rate of
epistaxis among the general population is about 60%, of which only 10% seeks
medical treatment. This factor is projected to restrain the growth of the
market during the forecast period.
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