Longevity &
Anti-senescence Therapy Market: Introduction
Aging is characterized by a
progression in losing of physiological integrity and function over time. Aging
epigenetics refers to changes in gene expression that naturally occur during an
organismal lifespan without altering the DNA sequence. Chromatin epigenetics is
regulated by several enzymes, which collectively give rise to modifications in
DNA methylation and histone methylation/acetylation processes. During aging,
chromatin appears to be in a more active state, with an overall decrease in DNA
methylation, thus leading to more relaxed global gene expression. Senescent
cells are linked with many age-related diseases such as neurodegenerative
diseases (Alzheimer’s and Parkinson’s disease; AD and PD, respectively),
cataract, glaucoma, cardiovascular diseases (CVD, atherosclerosis, and
hypertension), chronic obstructive pulmonary disease (COPD), idiopathic
pulmonary fibrosis (IPF), diabetes type II, sarcopenia, osteoarthritis,
osteoporosis, and certain types of tumors. The development of science and
medicine has contributed to the increase in human lifespan. However, with
increase in life expectancy, an increase in incidence of age-related diseases
has been observed. Therefore, it is crucial to find an approach to prevent or
delay ageing and the onset of age-related diseases. The only non-genetic
approach that can extend longevity is dietary/calorie restriction (DR/CR). This
intervention involves a 20% to 40% reduction in calorie intake without causing
malnutrition and has been shown to be effective in several species including
yeast, fruit flies, nematodes, rats, dogs, and even primates.
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Key Drivers of
Global Longevity & Anti-senescence Therapy Market
Increase in
Geriatric Population Worldwide
The world’s geriatric population
continues to grow at an unprecedented rate. Today, 8.5% of people worldwide
(617 million) are aged 65 and over. According to a new report – ‘An Aging
World: 2015’, the percentage is projected to jump to nearly 17% of the world’s
population by 2050 (1.6 billion). According to the National Institutes of Health,
America’s 65-and-over population is projected to nearly double over the next
three decades, from 48 million to 88 million by 2050. The global population of
the people aged 80 and older is expected to more than triple between 2015 and
2050, growing from 126.5 million to 446.6 million. The population aged 80 and
above in some countries in Asia and Latin America is predicted to quadruple by
2050.
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Rise in Awareness
of Antiaging Products among Generation Y and Later Generations
Anti-wrinkle products are gaining
traction as they have formulation well suited to slower the aging process.
Major causes of wrinkles include the lack of essential nutrients in the body,
exposure to UV light and pollution for higher duration, smoking, dehydration,
and drugs, along with other genetic factors. Greater aging anxiety and higher
importance of appearance were related to greater likelihood of purchasing
anti-aging products.
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North America to
Hold Major Share of Global Longevity & Anti-senescence Therapy Market
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Key Players Operating in Global
Market
The global longevity &
anti-senescence therapy market is highly concentrated, due to strong presence
of a few key players. Several manufacturers hold major share in the market in
their respective regions. Leading players operating in the global longevity
& anti-senescence therapy market are:
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Global Longevity
& Anti-senescence Therapy Market: Research Scope
Global Longevity
& Anti-senescence Therapy Market, by Therapy
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Global Longevity
& Anti-senescence Therapy Market, by Application
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Global Longevity
& Anti-senescence Therapy Market, by Region
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North America
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Europe
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Asia Pacific
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Latin America
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Middle East & Africa
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