For the last few decades scientist have been researching the involvement of the immune system in cancer development to discover potential cure. Immune cells has been known to play an important role in regulating tumor progression, thus stimulating immune reactions towards tumors can be an attractive therapeutic targeting cancer. More and more clinical data has been shown positive signs of immunotherapy and cell therapy as potential cure for cancer.
Immunotherapies using checkpoint inhibitors such as of PD-1/PDL-1 inhibitors have already been proven successful in clinical trials. They block a mechanism that tumor cells use to hide from immune system. CAR-T cells therapy goes one step further by engineering the T cells themselves to enhance the response from the immune system against tumor cells.
